IND Enabling Activities
Our Data Shows:
MP101 and MP201 significantly improve Clinical Scores (block paralysis) in the gold standard EAE model.
MP101 and MP201 prevents demyelination and destruction of the axon in the autoimmune independent cuprizone model.
MP101 and MP201 have a striking effect in preserving body movement and behavior compared to placebo (video).
Video of Multiple Sclerosis mouse model with MP101 and MP201.
MP101 and MP201 attenuates Multiple Sclerosis using the EAE Model.
*P values by Ordinal Regression
MP101 5mpk = 0.0192
MP201 80mpk = 0.00014
MP101 and MP201 Protect of Axons in Cuprizone Model.
MP101 and MP201 has a striking effect protecting against both demyelination and axonal loss in the autoimmune independent cuprizone model compared to placebo.